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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP2
All Species:
26.67
Human Site:
S898
Identified Species:
45.13
UniProt:
P29144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29144
NP_003282.2
1249
138350
S898
Q
I
R
H
E
Q
I
S
D
L
E
R
L
K
D
Chimpanzee
Pan troglodytes
XP_001151602
1249
138350
S898
Q
I
R
H
E
Q
I
S
D
L
E
R
L
K
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64514
1262
139860
S898
Q
I
R
H
E
Q
I
S
D
L
D
R
L
K
D
Rat
Rattus norvegicus
Q64560
1249
138274
S898
Q
I
R
H
E
Q
I
S
D
L
D
R
L
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513544
1367
152093
S1003
Q
I
R
H
E
Q
T
S
D
L
D
R
L
K
D
Chicken
Gallus gallus
XP_425591
1248
138209
S897
Q
I
R
H
E
Q
N
S
E
L
D
R
I
K
D
Frog
Xenopus laevis
NP_001085380
1261
139671
S899
Q
V
R
H
E
Q
I
S
E
L
E
R
L
K
D
Zebra Danio
Brachydanio rerio
XP_693179
595
63935
G265
V
T
S
G
G
A
H
G
T
H
V
A
S
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K1
1441
158719
D1013
Q
V
R
H
E
K
R
D
L
L
E
K
I
S
E
Honey Bee
Apis mellifera
XP_395521
1450
161968
K906
I
H
I
R
H
E
K
K
D
L
L
D
R
L
T
Nematode Worm
Caenorhab. elegans
Q09541
1374
151070
Q954
Q
I
R
Y
P
D
D
Q
V
L
Q
G
M
K
E
Sea Urchin
Strong. purpuratus
XP_788834
1215
133209
R885
D
K
G
D
Y
T
L
R
L
Q
V
R
H
D
R
Poplar Tree
Populus trichocarpa
XP_002318216
1299
143140
L939
R
H
D
N
V
Q
Y
L
E
K
M
K
Q
L
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193817
1380
152349
L1018
L
R
H
E
N
V
E
L
L
E
K
L
K
Q
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
N.A.
N.A.
95.3
96.8
N.A.
81.2
86
80.4
37.7
N.A.
34
41.3
35
54.7
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
97.4
98.7
N.A.
86.6
94.6
91.3
43.1
N.A.
53
59.2
53.4
71.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
93.3
93.3
N.A.
86.6
73.3
86.6
0
N.A.
40
13.3
33.3
6.6
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
93.3
93.3
100
0
N.A.
73.3
20
60
13.3
Percent
Protein Identity:
38
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
56.9
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
8
8
8
43
0
29
8
0
8
50
% D
% Glu:
0
0
0
8
58
8
8
0
22
8
29
0
0
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
0
0
8
0
0
0
8
0
0
0
% G
% His:
0
15
8
58
8
0
8
0
0
8
0
0
8
0
0
% H
% Ile:
8
50
8
0
0
0
36
0
0
0
0
0
15
8
0
% I
% Lys:
0
8
0
0
0
8
8
8
0
8
8
15
8
58
0
% K
% Leu:
8
0
0
0
0
0
8
15
22
72
8
8
43
15
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
65
0
0
0
0
58
0
8
0
8
8
0
8
8
0
% Q
% Arg:
8
8
65
8
0
0
8
8
0
0
0
58
8
0
8
% R
% Ser:
0
0
8
0
0
0
0
50
0
0
0
0
8
8
0
% S
% Thr:
0
8
0
0
0
8
8
0
8
0
0
0
0
0
8
% T
% Val:
8
15
0
0
8
8
0
0
8
0
15
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _